Short stature of men (157cm) and women (146cm).
	Abnormal ratio of extremities to one's trunk.
	Skin becomes thing, dry, and loses pigmentation.
	Hair grays and eventually diminishes.
	Underdeveloped sexual organs.
	Sharpening and thinning of nose.
	Occasionally develop high-pitched or hoarse voices.
	Cease of growth around age 14.
	Other symptoms that are common among aging (ulcers, cataracts, osteoporosis, etc).

Unfortunately there is currently no treatment in preventing this disorder.  Patients commonly expire around age 46 from malignant tumors or atherosclerosis.