Intro/Nervous System

In order to understand Parkinson’s and what it does and why certain symptoms occur, you need to understand the nervous system and how it works. The nervous system is the most complicated and fragile of all the body systems. It is the connection between the brain and the body. The nervous system allows us to move on command, to make smooth, precise movements. It is an intricate network of different instruments our body uses in unison to communicate what the mind wants the body to do (http://www.emc.maricopa.edu/faculty/farabee/BIOBK/BioBookNERV.html).

Its starts with the striatum; the central area of the brain. The striatum works with many other parts of the brain one of the more important pieces is the substantia nigra (in this case for balance and coordination). The two work together to send commands that go from the brain to the spinal cord and eventually too its final destination.

The nervous system is a web of nerves Nervous Systemand the spine is the main highway in which messages are carried through the nerves to other parts of our body branching from the spine. There are many neurotransmitters, which relay the messengers and their messages from nerve cell to nerve cell through out the body. One of the more important transmitters is called dopamine (created in the substantia nigra), which is vital in human movement. Dopamine in balance with another transmitter called acetylcholine which will be reviewed later, makes sure there is no unwanted movement and that the muscle moves smoothly and purposefully.

When a dopamine message is needed, the nerve cell gathers dopamine packets (within itself). The dopamine particles are then discharged from the end of the cell and across the synapse (the space between nerve cells) to another nerve cell. Pockets on the receiving cell collect the dopamine. A chemical called MAO-B, which hangs out around the synapse, breaks down any extra dopamine that did not originally fit the pockets. This is a crucial step in the wanted control of the muscle. Too much or too little dopamine creates problems and may create “unsmooth” muscle movement, like stuttering. The dopamine will eventually reach its destination and will then send the message of what the brain wants the body to do, thus creating thought into motion.

There is one other neurotransmitter mentioned earlier, which works in unison with dopamine, it is called acetylcholine. Depending on what your brain wants to do, it sends a specific balance of acetylcholine and dopamine. It is especially important in the smooth movement of our body. This is where a major problem of Parkinson’s occurs along with process’ earlier in the operation of movement com(http://www.parkinsonsinfo.com/about_parkinsons).